Eukaryotic NAT genes (fungi & protists only)
Updated List (2024)
For additional NAT genes annotated in eukaryotes, see here
Note 1: There is some overlap in the annotations of this and the original list, and those updated sequences are indicated with red font.
FUNGI
Organism Scientific Name	Organism identification code	Taxonomy identifier	Gene	ORF (bp)	Protein (aa)	Number of introns	Exon span
Ascomycota
Alternaria alternata strain SRC1lrK2f	ALTAL	5599	NAT1	924	307	0	1(924)
Aspergillus aculeatus ATCC 16872	ASPA1	690307	NAT1	960	319	2	1(1-408) 2(488-533) 3(627-532)
Aspergillus bombycis strain NRRL26010	ASPBO(NRRL26010)	109264	NAT1	981	326	2	1(1-426) 2(483-529) 3(588-1095)
			NAT2	957	318	1	1(1-396) 2(448-1008)
			NAT3	1014	337	1	1(1-420) 2(466-1059)
Aspergillus calidoustus	ASPCI	454130	NAT1	978	325	2	1(1-425) 2(481-528) 3(573-1077)
			NAT2	978	325	2	1(1-419) 2(492-539) 3(619-1129)
Aspergillus costaricaensis CBS 115574	ASPCO	1448317	NAT1	981	326	0	1(978)
Aspergillus glaucus CBS 516.65	ASPGL(CBS 516.65)	1160497	NAT1	948	315	2	1(1-395) 2(450-498) 3(553-1056)
Aspergillus homomorphus CBS 101889	ASPHC	1450537	NAT1	972	323	0	1(972)
Aspergillus kawachii IFO 4308	ASPKW	1033177	NAT1	1047	348	0	1(1-1047)
			NAT2	987	328	1	1(1-438) 2(502-1050)
			NAT3	948	315	1	1(1-372) 2(429-1004)
			NAT4	882	293	2	1(1-331) 2(513-558) 3(619-1123)
			NAT5	975	324	0	1(1-975)
Aspergillus lentulus strain IFM 54703	ASPLE(IFM 54703)	293939	NAT1	963	320	2	1(1-410) 2(468-515) 3(575-1079)
			NAT2	948	315	1	1(1-378) 2(437-1006)
Aspergillus luchuensis CBS 106.47 misnomer: Aspergillus foetidus CBS 106.47	ASPLC	1137211	NAT1	987	328	1	1(1-438) 2(502-1050)
			NAT2	969	322	2	1(1-418) 2(514-559) 3(620-1124)
			NAT3	975	324	0	1(1-975)
			NAT4	948	315	1	1(1-372) 2(429-1004)
Aspergillus neoniger CBS 115656	ASPNB	1448310	NAT1	1043	347	0	1(1043)
Aspergillus niger An76	ASPNG(An76)	5061	NAT1	1044	347	0	1(1-1044)
			NAT2	981	326	1	1(1-432) 2(496-1044)
			NAT3	966	321	2	1(1-415) 2(497-542) 3(607-1111)
			NAT4	948	315	1	1(1-372) 2(428-1003)
			NAT5	975	324	0	1(1-975)
Aspergillus niger ATCC 1015	ASPNA	380704	NAT1	948	315	0	1(1-948)
			NAT2	957	318	2	1(1-406) 2(501-546) 3(603-1107)
			NAT3	945	314	1	1(1-369) 2(424-999)
			NAT4	975	324	0	1(1-975)
Aspergillus ochraceoroseus strain SRRC1432	ASPOC(SRRC1432)	138278	NAT1	957	318	2	1(1-404) 2(482-529) 3(585-1089)
Aspergillus oryzae RIB40	ASPOR	510516	NAT1	1047	348	0	1(1-1047)
			NAT2	1173	390	3	1(1-426) 2(482-528) 3(588-854) 4(905-1095)
			NAT3	957	318	1	1(10396) 2(450-1010)
Aspergillus parasiticus SU-1	ASPPU	1403190	NAT1	1047	348	0	1(1-1047)
			NAT2	981	326	2	1(1-426) 2(282-528) 3(588-1095)
			NAT3	957	318	1	1(1-396) 2(448-1008)
Aspergillus piperis CBS 112811	ASPPI(CBS 112811)	1448313	NAT1	987	328	0	1(987)
			NAT2	948	315	0	1(948)
Aspergillus pseudotamarii strain CBS 117625	ASPPS	132259	NAT1	924	307	0	1(924)
Aspergillus ruber CBS 135680 equivalent name: Eurotium rubrum CBS 135680 Aspergillus rubrum CBS 135680	ASPRB(CBS 135680)	1388766	NAT1	972	323	2	1(1-401) 2(457-513) 3(566-1079)
			NAT2	1008	335	0	1(1-1008)
Aspergillus vadensis CBS 113365	ASPVC	1448311	NAT1	1043	347	0	1(1043)
Aspergillus versicolor CBS 583.65	ASPVE(CBS 583.65)	1036611	NAT1	975	324	2	1(1-398) 2(446-517) 3(576-1080)
			NAT2	1005	334	2	1(1-416) 2(447-522) 3(584-1096)
			NAT3	999	332	1	1(1-401) 2(503-1100)
Aspergillus wentii DTO 134E9	ASPWE(DTO 134E9)	1073089	NAT1	1029	342	0	1(1-1029)
			NAT2	945	314	2	1(1-392) 2(443-490) 3(542-1046)
Aureobasidium pullulans EXF150	AURPU(EXF150 )	1043002	NAT1	1026	341	0	1(1026)
Baudoinia panamericana UAMH 10762	BAUPA	717646	NAT1	1056	351	0	1(1056)
Byssochlamys spectabilis strain CBS 101075	BYSSP	264951	NAT1	969	322	0	1(969)
Cercospora beticola strain 09-40	CERBT(09-40)	122368	NAT1	969	322	0	1(969)
			NAT2	1038	345	0	1(1038)
Diplodia corticola strain CBS 112549	DIPCO(CBS 112549)	236234	NAT1	1023	340	0	1(1023)
Exserohilum turcica Et28A	SETT2	671987	NAT1	1026	341	0	1(1026)
Fusarium acuminatum CS5907	FUSAM(CS5907)	1318461	NAT1	960	319	0	1(1-960)
Fusarium avenaceum strain Fa05001 (Gibberella avenacea)	FUSAV(Fa05001)	40199	NAT1	957	318	1	1(1-372) 2(429-1013)
			NAT2	960	319	0	1(1-960)
Fusarium camptoceras strain NRRL 13381	FUSCM(NRRL 13381)	57143	NAT1	1038	345	0	1(1-1038)
Fusarium fujikuroi IMI 58289 equivalent name: Gibberella fujikuroi IMI 58289	GIBF5	1279085	NAT1	1038	345	0	1(1-1038)
			NAT2	1008	335(partial)	0	1(1-8008)
			NAT3	963	320	1	1(1-366) 2(530-1126)
			NAT4	978	325(partial)	0	1(1-978)
Fusarium fujikuroi strain FGSC 8932	GIBFU (FGSC 8932)	5127	NAT1	1038	345	0	1(1-1038)
Fusarium fujikuroi strain KSU X-10626	GIBFU (KSU X-10626)	5127	NAT1	1038	345	0	1(1-1038)
			NAT2	963	320	1	1(1-366) 2(530-1126)
Fusarium graminearum (Gibberella zeae) strain CS3005	GIBZA(CS3005)	1450154	NAT1	1032	343	0	1(1-1032)
			NAT2	1023	340	0	1(1-1023)
Fusarium langsethiae strain Fl201059 type material: CBS 113234	FUSLA(Fl201059)	179993	NAT1	1032	343	0	1(1-1032)
			NAT2	1032	343	0	1(1032)
			NAT3	957	318	1	1(1-372) 2(431-1015)
			NAT4	960	319	0	1(1-960)
			NAT5	1005	334	2	1(1-33) 2(93-103) 3(153-1113)
Fusarium mangiferae strain MRC7560	FUSMA(MRC7560)	192010	NAT1	1038	345	0	1(1-1038)
			NAT2	957	318	1	1(1-372) 2(424-1008)
			NAT3	978	325	0	1(1-978)
Fusarium oxysporum Fo47	FUSOX(Fo47)	660027	NAT1	1053	350	0	1(1-1053)
			NAT2	963	320	0	1(1-1145)
			NAT3	1005	334	0	1(1-1005)
Fusarium oxysporum Fo5176	FUSOF	660025	NAT1	1053	350	0	1(1-1053)
			NAT2	957	318	1	1(1-372) 2(424-1008)
			NAT3	960	319(partial)	0	1(1-960)
			NAT4	1248	415	2	1(1-365) 2(587-1136) 3(1198-1530)
Fusarium oxysporum FOSC 3-a	FUSOX	909455	NAT1	963	320	1	1(1-366) 2(549-1145)
Fusarium oxysporum f. sp. cubense race 1	FUSC1	1229664	NAT1	1053	350	0	1(1-1053)
			NAT2	957	318	1	1(1-372) 2(424-1008)
			NAT3	963	320	1	1(1-366) 2(549-145)
			NAT4	960	319(partial)	0	1(1-960)
Fusarium oxysporum f. sp. cubense race 4	FUSC4	2502994	NAT1	1053	350	0	1(1-1053)
			NAT2	963	320	1	1(1-366) 2(549-1145)
			NAT3	960	319	0	1(1-960)
Fusarium oxysporum f. sp. conglutinans race 2 54008	FUSOX(f. sp. conglutinans race 2 54008)	1089457	NAT1	1053	350	0	1(1-1053)
Fusarium oxysporum f. sp. cubense tropical race 4 54006 equivalent name: F. oxysporum f. sp. cubense tropical race 4 II5	FUSC4	1089451	NAT1	957	318	1	1(1-372) 2(424-1008)
			NAT2	1005	334	0	1(1-1005)
Fusarium oxysporum f. sp. pisi HDV247	FUSOX	1080344	NAT1	1053	350(partial)	0	1(1-1953)
			NAT2	1008	360	0	1(1-1008)
Fusarium oxysporum f. sp. radicis-lycopersici 26381 equivalent name: F. oxysporum f. sp. radicis-lycopersici CL57	FUSOX	1089448	ΝΑΤ1	963	320	1	1(10366) 2(549-1145)
Fusarium oxysporum f. sp. raphani 54005	FUSOX	1089458	ΝΑΤ1	1053	350	0	1(1-1055)
Fusarium oxysporum f. sp. vasinfectum 25433	FUSOX	1089449	ΝΑΤ1	1053	350	0	1(1-1053)
			ΝΑΤ2	963	320	1	1(1-366) 2(549-1145)
			ΝΑΤ3	963	320	1	1(1-366) 2(549-1145)
			ΝΑΤ4	1005	334(partial)	0	1(1-1005)
Fusarium poae strain 2516	FUSPO(2516)	36050	ΝΑΤ1	1032	343	0	1(1-1032)
			ΝΑΤ2	960	319	0	1(1-960)
			NAT3	957	318	1	1(1-372) 2(429-1013)
Fusarium proliferatum ET1 equivalent name: Fusarium proliferatum var. proliferatum ET1	FUSPR	1227346	NAT1	1038	345	0	1(1-1038)
			NAT2	954	317	1	1(1-345) 2(400-1008)
			NAT3	963	320	1	1(1-366) 2(530-1126)
			NAT4	978	325	0	1(1-978)
Fusarium proliferatum NRRL 62905	GIBIN(NRRL 62905)	948311	NAT1	1038	345	0	1(1-1038)
			NAT2	957	318	1	1(1-372) 2(424-1008)
			NAT3	963	320	1	1(1-366) 2(530-1126)
			NAT4	978	325	0	1(1-978)
Fusarium pseudograminearum CS3096	FUSPC	1028729	NAT1	1032	343	0	1(1-1032)
			NAT2	957	318	1	1(1-372) 2(431-1015)
			NAT3	960	319	0	1(1-960)
			NAT4	990	329	1	1(1-372) 424-1041)
Fusarium subglutinans	GIBSU	42677	ΝΑΤ1	1038	345	0	1(1-1038)
Fusarium venenatum strain A3/5	FUSVE(A3/50	56646	ΝΑΤ1	1032	343	0	1(1032)
Neosartorya udagawae IFM 46973 synonym: Aspergillus udagawae	ASPUD(IFM 46973)	91492	NAT1	1047	348	0	1(1-1047)
			NAT2	963	320	2	1(1-410) 2(467-514) 3(574-1078)
			NAT3	948	315	1	1(1-396) 2(496-1007)
Penicillium expansum strain MD8	PENEN	27334	ΝΑΤ1	987	328	0	1(987)
Pyrenophora tritici-repentis	PYRTR	426418	ΝΑΤ1	1029	342	0	1(1029)
Ramularia collo-cygni strain URUG2	RAMCO(URUG2)	112498	ΝΑΤ1	1053	350	0	1(1053)
Sphaerulina musiva SO2202	SPHMS	692275	ΝΑΤ1	1059	352	0	1(1059)
			ΝΑΤ2	996	331	0	1(996)
Basidiomycota
Agaricus bisporus var. burnettii JB137-S8	AGABU	597362	NAT1	1077	358	3	1(1-236) 2(297-425) 3(490-746) 4(814-1268)
Amanita muscaria Koide BX008	AMAMU(Koide BX008)	946122	NAT1	1134	377	3	1(1-239) 2(309-436) 3(494-748) 4(806-1317)
			NAT2	1104	367	3	1(1-224) 2(286-415) 3(466-718) 4(785-1281)
			NAT3	1101	366	3	1(1-224) 2(283-412) 3(464-716) 4(767-1260)
Anthracocystis flocculosa PF-1 genbank synonym: Pseudozyma flocculosa PF-1	ANTFO(PF-1)	1277687	NAT1	1179	392	1	1(1-801) 2(1312-1688)
Calocera cornea HHB12733	CALEO(HHB12733)	1353952	NAT1	969	322	1	1(1-182) 2(236-1022)
			NAT2	1002	333	1	1(1-182) 2(242-1061)
Calocera viscosa TUFC12733	CALVF	1330018	ΝΑΤ1	963	320	1	1(1-182) 2(233-1013)
			ΝΑΤ2	-	283(partial)	-	-
Ceraceosorus bombacissynonym: Dicellomyces bombacis ATCC 22867	CERBO	401625	NAT1	879	292	3	1(1-347) 2(413-850) 3(931-941) 4(1351-1435)
Cutaneotrichosporon oleaginosus	CUTOL	879819	NAT1	861	286	0	1(1-861)
Cutaneotrichosporon oleaginosum strain IBC0246	CUTOL(IBC0246)	879819	NAT1	861	286	0	1(861)
Cylindrobasidium torrendii FP15055 ss-10	CYLTO(FP15055 ss-10)	1314674	NAT1	1068	355	3	1(1-227) 2(277-405) 3(465-733) 4(786-1228)
			NAT2	1062	353	3	1(1-277) 2(281-409) 3(469-731) 4(787-1229)
Dacryopinax primogenitus includes: Dacryopinax sp. MIN 862738 includes: Dacryopinax sp. DJM-731 SS1	DACPD	1858805	NAT1	963	320	1	1(1-182) 2(242-1022)
			NAT2	-	294(partial)	-	-
Fomitiporia mediterranea MF3/22	FOMME	694068	NAT1	1122	373	3	1(1-212) 2(309-444) 3(531-832) 4(902-1373)
Fomitopsis pinicola FP-58527 SS1	FOMPI	743788	NAT1	1167	388	3	1(1-269) 2(366-494) 3(575-826) 4(984-1500)
Galerina marginata CBS 339.88	GALM3	685588	NAT1	1116	371	3	1(1-230) 2(302-434) 3(489-744) 4(810 -1306)
Gloeophyllum trabeum ATCC 11539	GLOTA	670483	NAT1	918	305	1	1(1-357) 2(443-1003)
Jaapia argillacea MUCL 33604	JAAAR(MUCL 33604)	933084	NAT1	1143	380	3	1(1-248) 2(303-427) 3(487-746) 4(801-1300)
			NAT2	1062	353	3	1(1-224) 2(291-425) 3(488-747) 4(827-1269)
Kalmanozyma brasiliensis GHG001	KALBG	1365824	NAT1	1095	364	1	1(1-102) 2(200-1192)
Leucoagaricus sp. SymC.cos	LEUSP	1714833	NAT1	1044	347	3	1(1-224) 2(286-414) 3(478-738) 4(777-1206)
Malassezia sympodialis ATCC 42132	MALS4	1230383	ΝΑΤ1	825	274	0	1(1-825)
Melampsora larici-populina 98AG31	MELLP	747676	NAT1	1041	346	2	1(1-367) 2(501-920) 3(1002-1255)
Moniliophthora perniciosa FA553	MONPE	554373	NAT1	933	310	4	1(1-152) 2(210-338) 3(392-648) 4(697-807) 5(860-1143)
Moniliophthora roreri MCA 2997	MONRO	1381753	NAT1	1044	347	3	1(1-236) 2(295-432) 3(476-735) 4(785-1194)
			NAT2	1017	338	4	1(1-218) 2(275-403) 3(480-736) 4(801-920) 5(975-1267)
			NAT3	999	332	4	1(1-209) 2(267-395) 3(449-705) 4(754-864) 5(917-1209)
Mixia osmundae IAM 14324	MIXOS	764103	ΝΑΤ1	978	325	0	1(1-978)
			ΝΑΤ2	978	325	0	1(1-978)
Pleurotus ostreatus PC15	PLEOS(PC15)	1137138	NAT1	1077	359	3	1(1-221) 2(282-410) 3(466-722) 4(779-1248)
Puccinia sorghi	PUCSO	27349	NAT1	1080	359	1	1(1-826) 2(929-1182)
Puccinia striiformis f. sp. tritici PST-78 synonym: Puccinia striiformis 2K041-Yr9	PUCST( f. sp. tritici PST-78)	1165861	NAT1	1215	404	2	1(1-543) 2(626-1036) 3(1132-1392)
Puccinia triticina 1-1 BBBD Race 1	PUCT1	630390	NAT1	1020	339	2	1(1-354) 2(429-838) 3(952-1207)
Rhodotorula graminis WP1	RHOGW	578459	NAT1	1053	350	3	1(1-315) 2(393-574) 3(670-706) 4(773-1291)
Rhodororula sp. JG-1b	RHOJ1	1305733	NAT1	1077	358	2	1(1-374) 2(447-534) 3(591-1205)
Rhodotorula toruloides NP11 equivalent name: Rhodosporidium toruloides NP11	RHOT1	1130832	NAT1	1074	357	2	1(1-371) 2(429-581) 3(638-1187)
			NAT2	1029	342	1	1(1-521) 2(593-1100)
Schizopora paradoxa synonym: Hyphodontia paradoxa	SCHPD	27342	NAT1	1113	370	2	1(1-200) 2(249-384) 3(443-1219)
Sporisorium reilianum SRZ2	SPORE	999809	NAT1	1146	381	1	1(1-102) 2(168-1211)
Stereum hirsutum FP-91666 SS1 Other names: Stereum hirsutum SS1 Stereum hirsutum FP-9166	STEHR	721885	NAT1	1050	349	3	1(1-50) 2(115-244) 3(320-683) 4(766-1271)
Trichosporon asahii var. asahii CBS 2479	TRIAS	1186058	ΝΑΤ1	948	315	0	1(948)
Tulasnella calospora MUT 4182 equivalent name: Tulasnella calospora AL13/4D	TULCA(MUT 4182)	1051891	NAT1	1014	337	1	1(1-303) 2(360-1070)
			NAT2	768	255	1	1(1-139) 2(210-838)
Zoopagomycota
Conidiobolus coronatus NRRL 28638	CONC2	796925	NAT1	987	328	1	1(1-987)
PROTISTS
Organism Scientific Name	Organism identification code	Taxonomy identifier	Gene	ORF (bp)	Protein (aa)	Number of introns	Exon span
Apicomplexa
Theileria equi strain WA (synonym: Babesia equi strain WA)	THEEQ(WA)	1537102	NAT1	867	288	0	1(1-867)
Ciliophora
Oxytricha trifallax	OXYTI	1172189	NAT1	2274	757	1	1(1-45) 2(118-2346)
			NAT2	2046	681	2	1(1-45) 2(116-370) 3(681-2426)
			NAT3	2247	748	1	1(1-45) 2(116-2317)
Pseudocohnilembus persalinus	PSEPJ	266149	NAT1	681	226	3	1(1-257)2(456-563)3(711-1018)4(1152-1159)
Stylonychia lemnae	STYLE	5949	NAT1	1026	341	0	1(1-1026)
Mycetozoa/Dictyosteliida
Dictyostelium purpureum strain QSDP1	DICPU(QSDP1)	5786	NAT1	885	294	0	1(1-885)
			NAT2	870	289	0	1(1-870)
			NAT3	948	315	0	1(1-948)
			NAT4	-	119(partial)	-	-
Dictyostelium fasciculatum SH3	CAVFA	1054147	NAT1	867	288	0	1(1-867)
			NAT2	840	279	0	1(1-840)
			NAT3	633	210	1	1(1-525) 2(666-773)
			NAT4	657	218	1	1(1-651) 2(797-802)
			NAT5	1179	392	0	1(1-141) 2(722-1429)
Dictyostelium lacteum strain TK (Tieghemostelium lacteum)	TIELA(TK)	361077	NAT1	927	308	0	1(1-927)
			NAT2	837	278	0	1(1-837)
			NAT3	768	255	0	1(1-768)
			NAT4	867	288	0	1(1-867)
Acytostelium subglobosum LB1	ACYSU(LB1)	1410327	NAT1	801	266	0	1(1-801)
Discosea/Centramoebida
Acanthamoeba castellanii strain Neff	ACACA(Neff)	1257118	NAT1	1089	362	4	1(1-285)2(370-439)3(514-894)4(986-1138)5(1223-1422)
Euglenozoa
Crithidia mellificae	CRIME	796356	NAT1	1125	374	0	1(1-1125)
Leptomonas seymouri	LEPSE	5684	NAT1	1113	370	0	1(1-1113)
Leptomonas pyrrhocoris	LEPPY	157538	NAT1	1119	372	0	1(1-1119)
Oomycetes
Aphanomyces astaci strain APO3	APHAT(APO3)	112090	NAT1	954	317	1	1(1-445) 2(502-1010)
Pelagophyceae
Aureococcus anophagefferens	AURAN	44056	NAT1	819	272	0	1(1-819)
This table was assembled by Maria-Aggeliki Tsatiri, Democritus University of Thrace, Greece.
The NAT sequences were retrieved from NCBI's Genome database and annotated by:
[1] Arvaniti K. (2020). Laboratory and computational investigation of the various functions of the NAT gene homologues in microorganisms. B.Sc Thesis, Democritus University of Thrace, Alexandroupolis, Greece.
[2] Kontomina E. (2020).Functional investigation of NAT genes in bacteria and fungi of biotechnological interest. PhD Thesis. Democritus University of Thrace, Alexandroupolis, Greece.
[3] Tsatiri M.A. (2021). Analysis of microbial NAT genes. B.Sc Thesis, Democritus University of Thrace, Alexandroupolis, Greece.
[4] Boukouvala S. (2024). Democritus University of Thrace, Alexandroupolis, Greece.